The work described within this thesis outlines the development

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steroids for men AbstractQuadrupolar oligothiophene chromophores composed of four to five thiophene rings with two terminal (E) dimesitylborylvinyl groups (4V 5V), and five thiophene rings with two terminal aryldimesitylboryl groups (5B), as well as an analogue of 5V with a central EDOT ring (5VE), have been synthesized via Pd catalyzed cross coupling reactions in high yields (66 89%). Crystal structures of 4V, 5B steroid, bithiophene 2V, and five thiophene derived intermediates are reported. Chromophores 4V, 5V, 5B and 5VE have photoluminescence quantum yields of 0.26 0.29, which are higher than those of the shorter analogues 1V 3V (0.01 0.20), and short fluorescence lifetimes (0.50 1.05ns). steroids for men

side effects of steroids The current advances of nanotechnology in medicine and biology open new horizons towards the development of novel tools (nanosensors) for the detection of several biological compounds, disease biomarkers and cellular molecules. Fluorescent nanosensors are utilised as efficient, rapid and sensitive probes in many analytical and biological applications. The small size of nanosensors enables their insertion into live cells, with minimal cellular disturbance, to detect a specific target within the intracellular environment in real time.The work described within this thesis outlines the development of fluorescent nanosensors for the detection of cellular and biological markers. side effects of steroids

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