However, it does reduce the number of relapses and

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The CONFIRM study run by Biogen shows that dimethyl fumarate (here called BG 12) at either of two oral dosage regimens is no better at preventing disability progression than placebo or daily injections of glatiramer acetate in relapsing remitting MS. However, it does reduce the number of relapses and particularly the appearance of new MRI lesions. So if you were an MS patient without a personal MRI facility, you would notice nothing, as you would be unaware of the statistical reduction in relapses but very aware of progressive disability.

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